Accepted | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002

Books/Chapters | Patents | Conferences/Symposiums Abstracts

Citations and h-index = 27

Accepted

(59) Goodwin, J.; Choi, H.; Hsieh, M-H.; Neugent, M. L.; Ahn, J-M.; Hayenga, H. N.; Singh, P. K.; Shackelford, D. B.; Lee, I-K.; Shulaev, V.; Dhar, S.; Takeda, N.; and Kim, J-W. "Targeting hypoxia-inducible factor-1α/pyruvate dehydrogenase kinase 1 axis by dichloroacetate suppresses bleomycin-induced pulmonary fibrosis"
Am. J. Respir. Cell. Mol. Biol., 2017, In Press. Link

2017

(58) Banik, B.; and Dhar, S. "Centrifugation free magnetic isolation of functional mitochondria using paramagnetic iron oxide nanoparticles"
Curr. Protoc. Cell Biol., 2017, 76, 25.4.1-25.4.20. Link

(57) Marples, B.; and Dhar, S. "Radiobiology and the renewed potential for nanoparticles"
Int. J. Radiation Oncol. Biol. Phys., 2017, 98, 489-491. Link

(56) Pathak, R. K.; Wen, R.; Kolishetti, N.; and Dhar, S. "A prodrug of two approved drugs, cisplatin and chlorambucil, for chemo war against cancer "
Mol. Cancer Ther, 2017, 16, 625-636. Link

2016

(55) Banik, B.; Askins, B. W.; and Dhar, S. "Mito-magneto: a tool for nanoparticle mediated mitochondria isolation"
Nanoscale, 2016, 8, 19581-19591. Link

(54) Basu, U.; Banik, B.; Wen, R.; Pathak, R. K.;and Dhar, S. "The platin-x series: activation, targeting, and delivery "
Dalton Trans., 2016, 45, 12992-13004. Link

(53) Wen, R.; and Dhar, S. "Turn up the cellular power generator with vitamin E analogue formulation "
Chem. Sci., 2016, 7, 5559-5567.Link

(52) Wen, R.; Umeano, A. C.; Francis, L.; Sharma, N.; Tundup, S.; and Dhar, S. "Mitochondrion: a promising target for nanoparticle-based vaccine"
Vaccines 2016, 4(2), 18. Link

(51) Pathak, R. K. and Dhar, S. "Combined chemo-anti-inflammatory prodrugs and nanoparticles"
Synlett, 2016, 27, 1607-1612.Link

(50) Chaudhary, A.; Bhat, T.; Kumar, S.; Kumar, A.; Kumar, R.; Underwood, W.; Koochekpour, S.; Shourideh, M.; Yadav, N.; Dhar, S.; Chandra, D "Mitochondria dysfunction-mediated apoptosis resistance associates with defective heat shock protein response in african american men with prostate cancer"
Br. J. Cancer, 2016, 114, 1090-1100. Link

(49) Wen, R.; Banik, B.; Pathak, R. K.; Kumar, A.; Kolishetti, N.; and Dhar, S. "Nanotechnology inspired tools for mitochondrial dysfunction related diseases"
Adv. Drug Deliv. Rev., 2016, 99, 52-69. Link

(48) Pathak, R. K. and Dhar, S. "Unique use of alkylation for chemo-redox activity by a Pt(IV) prodrug"
Chem. Eur. J., 2016, 22, 3029-3036. Link

(47) Kalathil, A. A.; Kumar, A.; Banik, B.; Ruiter, T. A.; Pathak, R. K.; and Dhar, S. "New formulation of old aspirin for better delivery"
Chem. Commun., 2016, 52, 140-143. Link

2015

(46) Feldhaeusser, B.; Platt, S. R.; Marrache, S.; Kolishetti, N.; Pathak, R. K.; Montgomery, D. J.; Reno, L. R. Howerth, E.; and Dhar, S. "Evaluation of Nanoparticle Delivered Cisplatin in Beagles"
Nanoscale, 2015, 7, 13822-13830. Link

(45) Pathak, R. K.; and Dhar, S. "A nanoparticle cocktail: Temporal release of predefined drug combinations"
J. Am. Chem. Soc., 2015, 137, 8324-8327. Link

(44) Pathak, R. K.; Kolishetti, N.; and Dhar, S. "Targeted nanoparticles in mitochondrial medicine"
WIREs Nanomed. Nanobiotechnol., 2015, 7, 315-329. Link

(43) Marrache, S.; Tundup, S.; Harn, D. A.; and Dhar, S. "Ex vivo generation of functional immune cells by mitochondria-targeted photosensitization of cancer cells", Weissig V. and Edeas M. Eds. In
Mitochondrial Medicine, Methods in Molecular Biology, Springer, New York, 2015, Vol 1265, 113-22. Link

(42) Marrache, S.; Pathak, R. K.; and Dhar, S. "Formulation and optimization of mitochondria-targeted polymeric nanoparticles", Weissig V. and Edeas M. Eds. In
Mitochondrial Medicine, Methods in Molecular Biology; Springer, New York, 2015, Vol 1265, 103-12. Link

(41) Hung, S. W.; Marrache, S.; Cummings, S.; Bhutia, Y. D.; Mody, H.; Hooks, S. B.; Dhar, S. and Govindarajan, R. " Defective hCNT1 transport contributes to gemcitabine chemoresistance in ovarian cancer subtypes: Overcoming transport defects using a nanoparticle approach"
Cancer Lett., 2015, 359, 233-240. Link

(40) Marrache, S.; and Dhar, S. "The energy blocker inside the power house: Mitochondria targeted delivery of 3-bromopyruvate"
Chem. Sci., 2015, 6, 1832-1845. Link

2014

(39) Marrache, S.; Pathak, R. K.; and Dhar, S. "Detouring of cisplatin to access mitochondrial genome for overcoming resistance"
Proc. Natl. Acad. Sci. USA, 2014, 111, 10444-10449. Link

(38) Pathak, R. K.; McNitt, C. D.; Popik, V. V. and Dhar, S. "Copper-free click-chemistry platform to functionalize cisplatin prodrugs"
Chem. Eur. J., 2014, 20, 6861-6865. Link

(37) Pathak, R. K.; Marrache, S.; Harn, D. A. and Dhar, S. "Mito-DCA: A mitochondria targeted molecular scaffold for efficacious delivery of metabolic modulator dichloroacetate"
ACS Chem. Biol., 2014, 9, 1178-1187. Link

(36) Pathak, R. K.; Marrache, S.; Choi, J. H.; Berding, T. B. and Dhar, S. "The prodrug Platin-A: Simultaneous release of cisplatin and aspirin"
Angew. Chem. Int. Ed., 2014, 53, 1963-1967. Link

2013

(35) Marrache, S.; Tundup, S.; Harn, D. A. and Dhar, S. "Ex vivo programming of dendritic cell by mitochondria-targeted nanoparticles to produce interferon-gamma for cancer immunotherapy"
ACS Nano, 2013, 7, 7392-7402. Link

(34) Hung, S. W.; Mody, H.; Marrache, S.; Bhutia, Y. D.; Davis, F.; Cho, J. H.; Zastre, J.; Dhar, S.; Chu, C. K. and Govindarajan, R. "Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: In vitro optimization and novel nanoparticle delivery studies"
PLOS ONE, 2013, 8(8), e71196. Link

(33) Marrache, S. Pathak, R. K.; Darley, K. L.; Choi, J. H.; Zaver, D.; Kolishetti, N. and Dhar, S. "Nanocarriers for tracking and treating diseases"
Curr. Med. Chem., 2013, 20, 3500-3514. Link

(32) Marrache, S. and Dhar, S. "Biodegradable synthetic high-density lipoprotein nanoparticles for atherosclerosis"
Proc. Natl. Acad. Sci. USA, 2013, 110, 9445-9450. Link

(31) Marrache, S.; Choi, J. H.; Tundup, S.; Zaver, D.; Harn, D. A. and Dhar, S. "Immune stimulating photoactive hybrid nanoparticles for metastatic breast cancer"
Integr. Biol., 2013, 5, 215-223. Link

2012

(30) Marrache, S. and Dhar, S. "Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics"
Proc. Natl. Acad. Sci. USA, 2012, 109, 16288-16293. Link

2011

(29) Dhar, S.; Kolishetti, N.; Lippard, S. J. and Farokhzad, O. C. "Targeted delivery of cisplatin prodrug for safer and more effective prostate cancer therapy in vivo"
Proc. Natl. Acad. Sci. USA, 2011, 108, 1850-1855. Link

(28) Roy, M.; Dhar, S.; Maitya, B. and Chakravarty, A. R. "Dicopper(II) complexes showing DNA hydrolase activity and monomeric adduct formation with bis(4-nitrophenyl)phosphate"
Inorg. Chim. Acta., 2011, 375, 173-180. Link

2010

(27) Kolishetti, N.; Dhar, S.; Valencia, P.; Lin, L.; Karnik. R.; Lippard, S. J.; Langer, R. and Farokhzad, O. C. "Engineering of self-assembled nanoparticle platform for precisely-controlled combination drug therapy"
Proc. Natl. Acad. Sci. USA, 2010, 107, 17939-17944. Link

(26) Lee, T.; Zhang, X.; Dhar, S.; Faas, M. S.; Lippard, S. J. and Jasanoff, A. P. "In vivo imaging with a cell-permeable porphyrin-based MRI contrast agent"
Chem. Biol., 2010, 17, 665-673. Link

2009

(25) Dhar, S.; Daniel, W. L.; Giljohann, D. A.; Mirkin, C. A. and Lippard, S.J. "Polyvalent oligo-modified gold nanoparticles as delivery vehicles for platinum(IV) warhead"
J. Am. Chem. Soc., 2009, 131, 14652-14653. Link

(24) Dhar, S. and Lippard, S. J. "Mitaplatin, A Potent Fusion of Cisplatin and the Orphan Drug Dichloroacetate"
Proc. Natl. Acad. Sci. USA, 2009, 106, 22199-22204. Link

2008

(23) Dhar, S.; Gu, F. X.; Langer, R.; Farokhzad, O. C. and Lippard, S. J. "Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles"
Proc. Natl. Acad. Sci. USA, 2008, 105, 17356-17361. Link

(22) Tennyson, A. G.; Dhar, S. and Lippard, S. J. "Syntheses of {Ni(NO)}10 and {Co(NO)2}10 complexes supported by thiolate ligands: Insight into the nitric oxide chemistry of iron thiolate complexes in biology"
J. Am. Chem. Soc., 2008, 130, 15087-15098. Link

(21) Dhar, S.; Liu, Z.; Thomale, J.; Dai, H. and Lippard, S. J. "Targeted single walled carbon nanotube mediated Pt(IV) prodrug delivery using folate as homing device"
J. Am. Chem. Soc., 2008, 130, 11467-11476. Link

(20) Roy, S.; Patra, A. K.; Dhar, S. and Chakravarty, A. R. "Photosensitizer in a molecular bowl and its effect on the DNA binding and cleavage activity of 3d-metal scorpionates"
Inorg. Chem., 2008, 47, 5625-5633. Link

2007

(19) Dhar, S.; Kodama, T. and Greenberg, M. M. "Selective detection and quantification of oxidized abasic lesions in DNA"
J. Am. Chem. Soc., 2007, 129, 8702-8703. Link

2006

(18) Dhar, S.; Nethaji, M. and Chakravarty, A. R. "DNA cleavage on photoexposure at the d-d band in ternary copper(II) complexes using red-light laser"
Inorg. Chem., 2006, 45, 11043-11050. Link

2005

(17) Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Steric protection of photosensitizer in a N,N-bis[2-(2-pyridyl)ethyl]-2-phenylethylamine-copper(II) bowl that enhances red light-induced DNA cleavage activity"
Inorg. Chem., 2005, 44, 8876-8883. Link

(16) Dhar, S. and Chakravarty, A. R. "Photosensitizer in a molecular bowl: Steric protection enhancing the photonuclease activity of copper(II) scorpionates"
Inorg. Chem., 2005, 44, 2582-2584. Link

(15) Patra, A. K.; Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Metal-assisted red light-induced DNA cleavage by ternary L-methionine copper(II) complexes of planar heterocyclic bases"
Dalton Trans., 2005, 896-902. Link

(14) Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Synthesis, crystal structure and photo-induced DNA cleavage activity of ternary copper(II) complexes of NSO-donor Schiff bases and NN-donor heterocyclic ligands"
Inorg. Chim. Acta., 2005, 358, 2437-2444. Link

(13) Gupta, T.; Patra, A. K.; Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Effect of copper-sulfur bond on the DNA photocleavage activity of 2-(methylthio) ethylpyridine-2-carbaldimine copper(II) complexes"
J. Chem. Sci., 2005, 117, 123-132. Link

(12) Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Effect of charge transfer bands on the photo-induced DNA cleavage activity of [1-(2-thiazolylazo)-2-naphtholato]copper(II) complexes"
J. Inorg. Biochem., 2005, 99, 805-812. Link

(11) Mukherjee, A.; Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Ternary iron(II) complex with an emissive imidazopyridine arm from Schiff base cyclizations and its oxidative DNA cleavage activity"
Dalton Trans., 2005, 349-353. Link

(10) Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Designing molecules for PDT: red light-induced DNA cleavage on disulfide bond activation in a dicopper(II) complex"
Dalton Trans., 2005, 344-348. Link

2004

(9) Pradhan, R.; Thomas, A. M; Mukherjee, A; Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Synthesis, crystal structute and DNA hydrolysis activity of ternary (N-salicylidene-L-methioninato)copper(II) complexes of heterocyclic bases"
Indian J. Chem., 2004, 43A, 2307-2314. Link

(8) Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Synthetic analogue approach for the functional domains of copper(II)-bleomycins and its DNA cleavage activity"
Dalton Trans., 2004, 4180-4184. Link

(7) Gupta, T.; Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Bis(dipyridophenazine)copper(II) complex as major groove directing synthetic hydrolase"
Dalton Trans., 2004, 1896-1900. Link

(6) Dhar, S.; Reddy, P. A. N. and Chakravarty, A. R. "Intramolecular nucleophilic activation promoting efficient hydrolytic cleavage of DNA by (aqua)bis(dipyrido-quinoxaline)copper(II) complex"
Dalton Trans., 2004, 697-698. Link

2003

(5) Patra, A. K.; Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Visible light-induced nuclease activity of a ternary mono-phenanthroline copper(II) complex containing L-methionine as a photosensitizer"
Chem. Commun., 2003, 1562-1563. Link

(4) Dhar, S.; Senapati, D.; Reddy, P. A. N.; Das, P. K. and Chakravarty, A. R. "Metal-assisted red light-induced efficient DNA cleavage by dipyridoquinoxaline- copper(II) complex"
Chem. Commun., 2003, 2452-2453. Link

(3) Dhar, S. and Chakravarty, A. R. "Efficient visible light-induced nuclease activity of a ternary mono-phenanthroline copper(II) complex containing 2-(methylthio)ethylsalicylaldimine"
Inorg. Chem., 2003, 42, 2483-2485. Link

(2) Dhar, S.; Senapati, D.; Das, P. K.; Chattopadhyay, P.; Nethaji, M. and Chakravarty, A. R. "Ternary copper complexes for photo-cleavage of DNA by red light: direct evidence for sulfur to copper charge transfer and d-d band involvement"
J. Am. Chem. Soc., 2003, 125, 12118-12124. Link

2002

(1) Dhar, S.; Reddy, P. A. N.; Saha, M. K.; Nethaji, M.; Mahadevan, S. and Chakravarty, A. R. "Effect of steric encumbrance of tris(3-phenylpyrazolyl)borate on the structure and properties of ternary copper(II) complexes having N,N-donor heterocyclic bases"
Inorg. Chem., 2002, 41, 3469-3476. Link

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Book Chapters

(3) Wen, R.; Umeano, A. C.; and Dhar, S. "Accessing mitochondrial targets using nanocargos", V. Weissig and A. Prokop, Eds. In
Intracellular Delivery III; Springer International Publishing, Switzerland, 2016, pp 229-254.Link

(2) Dhar, S. and Lippard, S. J. "Current status and mechanism of action of platinum-based anticancer drugs", E. Alessio Ed. In
Bioinorganic Medicinal Chemistry; Wiley-VCH, Weinheim, Germany, 2011, pp 79-95. Link

(1) Dhar, S. and Lippard, S. J. "Structural and mechanistic studies of anticancer platinum drugs: Uptake, activation, and the cellular response to DNA binding", A Bonetti et al. Eds. In
Platinum and other heavy metal compounds in cancer chemotherapy; Humana Press, NJ, 2009, pp 135-147. Link

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Patents

(18) Kalathil, A. A.; Banik, B.; Kumar, A.; and Dhar, S. "Modification of drugs for incorporation into nanoparticles",

U.S. Pat. Appl. Publ., 2017, US 20170087167 A1 20170330. Link

(17) Dhar, S.; and Pathak, R. K. "Platinum prodrugs and methods of making and using thereof",
PCT Int. Appl., 2016, WO 2016144889 A1 20160915. Link

(16) Dhar, S.; Marrache, S.; Wen, R.; and Banik, B. "Nanoparticles for lipid homeostasis",

PCT Int. Appl., 2016, WO 2016106328 A1 20160630. Link

(15) Dhar, S.; Wyatt, E. L.; Marrache, S. and West, F. D. "Therapeutic nanoparticles for accumulation in the brain",
PCT Int. Appl., 2016, WO 2016022462 A1 20160211. Link

(14) Dhar, S.; Pathak, R. K.; and Marrache, S. "Mitochondria-targeting platinum(IV) prodrug",
PCT Int. Appl., 2015, WO 2015157409 A1 20151015. Link

(13) Dhar, S.; and Marrache, S. "Mitochondrial delivery of 3-bromopyruvate",
PCT Int. Appl., 2015, WO 2015138992 A1 20150917. Link

(12) Dhar, S.; Pathak, R. K.; Popik, V. V.; McNitt, C. D. "Platinum(IV) compounds and methods of making and using same",
PCT Int. Appl., 2015, WO 2015134599 A2 20150911. Link

(11) Dhar, S.; and Pathak, R. K. "Produg for release of cisplatin and cyclooxygenase inhibitor",
PCT Int. Appl., 2015, WO 2015089389 A1 20150618. Link

(10) Dhar, S.; and Pathak, R. K. "Precise delivery of therapeutic agents to cell mitochondria for anti-cancer therapy",
PCT Int. Appl., 2015, WO 2015002996 A1 20150108. Link

(9) Dhar, S.; and Pathak, R. K. "Combination therapeutic nanoparticles",
PCT Int. Appl., 2014, WO 2014169007 A2 20141016. Link

(8) Dhar, S.; Marrache, S.; Harn, D. A.; and Tundup, S. "Generation of functional dendritic cells",
PCT Int. Appl., 2014, WO 2014124425 A1 20140814. Link

(7) Dhar, S. and Marrache, S. "Nanoparticles for mitochondrial trafficking of agents",
PCT Int. Appl., 2013, WO 2013123298 A1 20130822. Link

(6) Dhar, S. and Marrache, S. "Apoptosis-targeting nanoparticles",
PCT Int. Appl., 2013, WO 2013033513 A1 20130307. Link

(5) Dhar, S.; Choi, J. H. and Marrache, S. "Immune-stimulating photoactive hybrid nanoparticles",
PCT Int. Appl., 2013, WO 2013012628 A2 20130124. Link

(4) Farokhzad, O. C.; Kolishetti, N.; Dhar, S.; Lippard, S. J. and Langer, R. "Particles for multiple agent delivery",
PCT Int. Appl., 2011, WO 2011084620 A2 20110714 Link

(3) Mirkin, C. A.; Giljohann, D. A.; Daniel, W. L.; Lippard, S.J and Dhar, S. "Polyvalent polynucleotide nanoparticle conjugates as delivery vehicles for a chemotherapeutic agent",
PCT Int. Appl., 2011, WO 2011028847 A1 20110310.Link

(2) Lippard, S. J.; Dhar, S.; Farokhzad, O. C.; Kolishetti, N.; and Gu, F. X. "Nanostructures for drug delivery",
PCT Int. Appl., 2010, WO 2010047765 A2 20100429. Link

(1) Lippard, S. J. and Dhar, S. "Platinum (IV) complexes for use in dual mode pharmaceutical therapy",
PCT Int. Appl., 2010, WO 2010027428 A1 20100311. Link

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